| Date | Locaux | Visiteurs | ||
|---|---|---|---|---|
| 22/10/2021 17:30 |  | US Carcassonne | RC Vannes |  |
| 29/10/2021 17:30 | | US Carcassonne | SU Agen |  |
| 05/11/2021 18:30 |  | Colomiers Rugby | US Carcassonne | |
| 18/11/2021 23:00 | | US Carcassonne | FC Grenoble Rugby |  |
| 25/11/2021 23:00 |  | Aviron Bayonnais | US Carcassonne | |
| 02/12/2021 23:00 | | US Carcassonne | AS Béziers Hérault |  |
| 09/12/2021 23:00 |  | RC Narbonnais | US Carcassonne | |
| 16/12/2021 23:00 | | US Carcassonne | USON Nevers |  |
| 06/01/2022 23:00 |  | Stade Montois Rugby | US Carcassonne | |
| 13/01/2022 23:00 | | US Carcassonne | Oyonnax Rugby |  |
| 20/01/2022 23:00 |  | Rouen Normandie | US Carcassonne | |
| 27/01/2022 23:00 | | US Carcassonne | US Montalbanaise |  |
| 10/02/2022 23:00 | | US Carcassonne | US Bressane |  |
| 17/02/2022 23:00 |  | Provence Rugby | US Carcassonne | |
| 24/02/2022 23:00 | | US Carcassonne | RC Narbonnais | |
| 03/03/2022 23:00 | | RC Vannes | US Carcassonne | |
| 10/03/2022 23:00 | | SU Agen | US Carcassonne | |
| 31/03/2022 22:00 | | US Carcassonne | Colomiers Rugby | |
| 07/04/2022 22:00 | | USON Nevers | US Carcassonne | |
| 14/04/2022 22:00 | | US Carcassonne | Stade Aurillacois |  |
| 21/04/2022 22:00 | | FC Grenoble Rugby | US Carcassonne | |
| 05/05/2022 22:00 | | US Carcassonne | Aviron Bayonnais | |
| 12/05/2022 22:00 | | AS Béziers Hérault | US Carcassonne | |